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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8128faf9d3a72de7a79fb05e5826f3afc8229e162a6772e369ad8d9a8859c3c5' 
  AND token = 'ZMTkaaJAR0vfVXt84lgZ72FgsLMXDK8IQ/fJbE32zzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}