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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499aed6a0d37060556d1ac2f2da1b15cf9e251c2cdfdf6047b9386b9f4c0033c' 
  AND token = '2KmxA8l7kU8dRzCaCIyS9KddNmGBjzr1O5+edm09Y0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}