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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37abd62cc66363af294a5af76b3c2bdbde02f7ca559d3f88f662c2485aefa04c' 
  AND token = 'MB+0/7bnyOgWiFJa+vnvweHLWob4LEt4baX8ZcfqTPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}