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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab270631c25eb4699fa0d3d297d4293704f9aa25975e12a3ad806e16d93924b' 
  AND token = '+kqO+vx2mJMHvMIewcZByg4lAM2UUv3nylGSRt6pg9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}