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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e2e7e5411be9b5a03f0152b4f2ca9980490beb47187b077574eef212cdcade8' 
  AND token = 'SV/XJ9sxwhJMoxZ+I4U0DQZHYwhsX7BrUnp/8Xf2dKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}