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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356963d3133af53976104fe754cc22026f2a2e4d1cd86ac7739f3e4e9ceb03a3' 
  AND token = '1o6vHX9zj4Tda497+OnbVe87yxm0RAHcd/JqhQ4nL5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}