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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372784fa3c9779f44718e9e8c9d6c57e76ac1867c4029a89e680c618f44f1ac8' 
  AND token = 'b+3GGNZW+WM8oEz/QeSDUsgNNvDikO4CmX78A3NH388=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}