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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f58226f07a9c0d740b699a3fd99a9255aa8f9698b493f94c2a855e02cf0b6e2' 
  AND token = '6Wj9+11cEvzwzLI37oYGO+lpjWCiD4iur611FQb9tdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}