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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f924d09da6d01feb563a5c0a1814301a08d32a09911b09bd1b5a25dbae988fb6' 
  AND token = 'cQ6P8Prp+bUtwV1Yu1X4FTlgPtLHM7rog1+h2ctvpdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}