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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f0550da4a2c022d5984956c3de1fb6ff4f3851b5046e9b2e916274bf024c6b' 
  AND token = 'w3H6p6fe8Zm4nnAatGEkozBNZajzoL50axGBKcdBLZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}