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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df8d4d7506460b830f695aef3ec90378641127b2dc3a6dfc5c35cb6d407119f' 
  AND token = 'N96SME37vcCbHSh1TGEBE4PVSYAPz3X6b884jY7xSI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}