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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e02049c0e84b46c46dd15448b6bc30e4059dd8eb721ac35da89e5fd3b4152ead' 
  AND token = 'Lijyb+AOKRAnyK4CjTXVDpV6pCQw8/g0kfhgYmWQ9l0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}