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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e15f4eafc45b64f790ab31d90c63dfcc0e9bbbc7f07bd5d7b3f0b1011ff849' 
  AND token = 'H9CP9cFfmlurFSUEd8fg7tT5Ahkb9jRtGNiG/P0Q0R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}