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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31120ed4b52cd9e70fe5d0c2b226879adcac52d1ed1026be07addc8c8c5a7aa3' 
  AND token = 'Np6psxet7nnk3qrDf0afeJBDougV+3Ssmi658pn4W+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}