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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d85d0acad8bb102a740ffccc91c7ba423035748fe0c61542eb41d02959feb4' 
  AND token = 'SObL5MVeJORs7Oh2VVJ5ercJVNTnTJNIb7q2Ltf9rL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}