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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3bdbd662dd225c6fb78da311228d92462484a2afc800dd7a6795c10abded674' 
  AND token = 'a3f1yvo1CmTp2PmnM7cBtGatA24e4JcAHD6aAiFdK9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}