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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6d73ab5c386a81032be403c2cbf9c2eb676b88def64a0e1f328155730d242ed' 
  AND token = 'R5iL4HKAbbSd+EwVmzUUlv6jdYCkZTzhkGdZeFaIyP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}