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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47891dcd330f7c73c539cc815fdeaeb01804b32ab9ea694f268b4b18f0c408db' 
  AND token = 'A+SBHle/V3KIDrheQTdWj3SEOOaNIttuBI/JyvdxBUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}