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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a6a1279f433c3b4552a5cbaddf009350ead28b547cb0d6fb8fdd81a30dc1432' 
  AND token = '+rTTShM5jzjefh2ockG6jURcBNLA3oIysMigBjiedFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}