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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86230e5333fa95176c468da94332912da88c4e42e561ad9d6f505c3ec7a01c21' 
  AND token = 'RYEAMFW8kmw5Hr0ZjFvVVnpa3Pa9ETN71opvFPxCRe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}