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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b824ff0a6a9e88f67843a690f019f4084a92006b591a87d369856a116f36a6' 
  AND token = '/qSOfAM4FWK6qUvZ9kfVLWai31qMCewoJs/7lI2I8Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}