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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f55f4a47b2595ac5275e21e7490307508934489ede4bdb8795a20c11e781d85' 
  AND token = 'rImApRf7+JIIWDRT7vVbNoxIq7jS3zL/E+cVGH7esRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}