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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a50f80a39371d9b60c4e6c2f694f8b68345362dd4a6391f65d7f33d8ff37b59' 
  AND token = 'rzrpMSYN8exiRddl7eo4j1pgyCuy6ha1r5Jy3GTh08U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}