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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29ed611b85c917de52ceb8f80dae9fd50eb827031da82b8a7412ba74477a0bfd' 
  AND token = 'CdoZRG/k58tSgFZyjelllV4U/21d3VZh/s36eQWVudY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}