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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb058afb2dca17422b095e9a74c1c617be40c8928fdedcfdad451c81dabbd6f' 
  AND token = 'WJDFj+u8KGSVwciCfM1jICmDqEXhN2KoUZdEU9XSXFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}