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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0487e736f7945ef8579a2ccf25933545b4b4b5ee8c0c0b7ddc2683c564531246' 
  AND token = 'Rw+PtcBidhRMyG98B9HAkUXl0FTNa1GJTE0h8CeKUiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}