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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5caec49030533054673d14f4389bb426fdc6a9fd7c0c6f1a6bbf60abd625641c' 
  AND token = '3w7pTUqX/RRGAWPC9ARopZ5h8M8Q0SwCHMNc16pcaNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}