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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5c943e1c6bbea1289a741cae88ba06d97d2f8f8237afbcb12f3ef8ef8b6527f' 
  AND token = 'dmB9o1aPxqFJW0VKdE69yHYXFpA3t8cb17QlKUcGqXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}