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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bcaf61165e581a2256795c8e2e053f96ed45adba9777a6c9ab3aede4b0fba235' 
  AND token = '1ucKFSrRedDGUuKUF20p+m88R6NqFCYDaathuPBY3xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}