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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b21f62690acaca48000928a6a4b9e6c2dd6076a790ddcfb653c2e5c98e8238' 
  AND token = '6EXR771C0d3fwdK/sljFtzrH4uGAxOhO1j8A8xzaTxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}