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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ac55d2b44577d38140581c954c0ef426b1cd3ac470eaaba63c2a91ffeb735d1' 
  AND token = 't4U+sv6d4PEznkSvwjDaFeQKKxEAIV6tUm6DGznV+Mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}