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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8dc82c0f698d2a63f02b1a0e03cf5a848a51ff1a8457081917e8721a1e0ac66' 
  AND token = 'aG15k537Zb72XecOcLOiQlZxLQmvGG6WO29UA5bzXt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}