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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4b61b7536c4b6c02aa86db567cccdf06783d8286929f85f8b529fc9166adb01' 
  AND token = 'J+Psmqj0VKx6b2iaq7N/7rDMkcoUjWZ0m4rX79qBw5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}