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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7300cecb326f5bb4641d6670ade8edb874d2177eb13f8db126ed7bf7946e3b07' 
  AND token = 'iC73yMJPgUPsNMtw4rrG3EHiHTKGy5WohCTp9KDQhiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}