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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d47f26f5bebf6c16f51424169e91c71d8a7571b1e049da79be6acfff0ffc40' 
  AND token = 'tFTSLMo76OuaZfSpY31N5htbdSUv155UDGw+W72Aj7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}