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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '365b4fbe65cfdc169ec9733fe6908ba8370a005c7506279a48ecee8b45bc5981' 
  AND token = '3HArb4tGLKg9jtmRAvzols+hUiojcVOwx6AWPiCbhZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}