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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b43bc1c4ee505512a0d5e9fea4435bbe502160815cca7c1115d466ae5200670' 
  AND token = 'B1kRvTpPxXDd2W1aZYSB3sazCBovsoLjienyDKL0rJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}