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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2420c0c483c7c28a29b14cdb7d56a399abb15ab365421488cb9ca48a36f0704' 
  AND token = 'S4riRrZLamUcFHrWz+SmgWg8bNJWDsUS5IRIJwOTa5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}