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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6cd409ecf0560a0295d9c2a9054c19859690d7b1a84badd09d180179a622ca1' 
  AND token = 'M8R7K7dKGZXAqL9T/4uFe9FFgoq8S+pbeBqI7oZrf4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}