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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b341ea0684f5cd3c5467c044b041b3b5b1dad8785b96981616686c7de9a94f28' 
  AND token = 'zPVkkgTYwsNagSaB4xJn4kHwgGx37jnHX5DmqHIZeSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}