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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e7f4509b0eb72632d97235d44f6eb9f6f8955eb8ff657e0237addfdae0bce0' 
  AND token = 'ToiM5UOUkBKpuB+bqgdUEarLbrCvUSVAmkGz7F653WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}