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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6398e541a0080612419f7e3be24dc3bbf3ab74ebbb374df6eaecc2251023ea77' 
  AND token = 'IWmnjyxE9R6ly5SJ7FBY5GGO9KjzMQzA1manmaz1sAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}