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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e207bee4a48e24838daddb31bded6fad37e712a4200a69e8adf39d6ca6fdc6' 
  AND token = 'fKhTSRrSoE2R1zAwuUEvpzYSIYsnjxDk03ZhkWwITH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}