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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2c5794eb8b23a3fa89e480abbafd2478ec26d6c45cf97c3108e73ddbe7ee49' 
  AND token = 'affnDoZKDl4t3duq7qfdwGv1nFHlW+MNDM+t7OJyMI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}