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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b8a4a3c12ebd96b6faa522be80609354672bc19e716cdfa7678c85a2c49b6c7' 
  AND token = '2tyEC3hW0l/gqUjsoApiqrLbs8icm5h/X4Rb0Cq+fJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}