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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c04dd602be15a6883d91e18c971c8dce888e308cce3241f905134703b03b6f1' 
  AND token = '6wvtVWOMBnOda3YQaJVSrCJXxb631AmlqOuhOaep/Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}