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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecf0cc69a84b8e11c260a917ce8097b2b2e2e157ea8075fb973de97f2403e351' 
  AND token = 'kLMmuQvQlN4OZGXibf5qd5+6a8syz5fMLdSR5HVjNeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}