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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cf04b437e97b36ffbf37ba37db1a903469118fe649caf6bf85258b82fba6dba' 
  AND token = '4Hgw1dboh2pCH3O/TxCN/tAjgIcVGN8mErwbeHX7LFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}