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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccfb488bc126b537f6eac411c3e25eee07a72368d9bfa2e5759e95b40423a0fa' 
  AND token = '8UZQqBBBDePQSn67BSULd9R7eKNcz5DOyCKetmEF43g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}