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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ebf66d6fb9a88c6522f6bba7fc27d289487c8f65666844bd93a780af06f4f92' 
  AND token = '7k3IPurCEl0NAEDK454VUO1fr7c2fhzqURUjI1WrJ90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}